Frequently Asked Questions

ISRIB A15 is an enhanced analogue of the original ISRIB compound, designed with improved bioavailability and potency. It targets the eIF2B complex to inhibit the integrated stress response (ISR), potentially restoring cognitive function that has been impaired by stress, aging, or injury. A15 is specifically optimized for oral administration and research applications.

ISRIB works by targeting the integrated stress response (ISR) in cells. When neurons are under stress, the ISR acts like a brake on protein synthesis, which is essential for memory formation. ISRIB releases this brake by enhancing eIF2B function, allowing neurons to resume normal protein production and potentially restore cognitive abilities.

ISRIB A15 is a more potent analog with enhanced pharmacokinetic properties. While the original ISRIB requires larger doses and has limited oral bioavailability, A15 achieves similar effects at lower doses (5–15 mg vs 50+ mg) and is better suited for oral administration. A15 also has improved stability and solubility.

All our compounds are ≥98% purity, verified through independent third‑party testing using HPLC, NMR, and mass spectrometry.

These are research chemicals intended for laboratory use only. While animal studies have shown promising safety profiles, these compounds have not been approved for human consumption. Handle only by qualified researchers following proper safety protocols.

Store at −20 °C in a dry, light‑protected environment. Use desiccant to prevent moisture. Allow vials to reach room temperature before opening to avoid condensation. Properly stored compounds maintain stability for 2+ years.

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Cryptocurrency (USDT, BTC), bank transfers (SEPA/SWIFT), and Wise. We arrange the method individually for speed and privacy.

Yes — we offer custom synthesis and bulk production. Send your requirements for a quote and timeline.

Yes, significant discounts are available for bulk orders (>10 g) and institutional purchases.

Absolutely. All payment details are handled via encrypted channels. We don’t store sensitive payment data.

Yes — we provide invoices and documentation required by universities and research institutions.

Typically 5–15 business days, depending on destination: Europe 5–10, North America 7–12, Australia/Asia 10–15. Express options available. All orders include tracking.

Yes — we ship to 50+ countries. We manage customs paperwork and ensure compliance. Packaging is discreet.

Orders are packed discreetly with proper labeling and safety information. Temperature‑sensitive items include cold packs when needed.

Shipments are tracked and insured. If a package is lost or damaged, we will promptly send a replacement at no extra cost.

Yes, we frequently ship to universities and labs. We coordinate with receiving departments and provide all required documents.

Some countries restrict certain research chemicals. We’ll advise on restrictions and alternatives for your location.