C₁₁H₂₀N₂O₄
Rapid-acting research compound that disrupts the SERT–nNOS interaction. Research use only.
ZZL‑7 represents a breakthrough in rapid‑acting research compounds. Unlike traditional approaches that can take weeks to show effects, ZZL‑7 disrupts the SERT‑nNOS protein interaction in the dorsal raphe nucleus, leading to fast‑onset responses in research models.
This compound has opened new avenues for understanding rapid‑acting mechanisms and has become an essential tool for researchers studying fast‑onset behavioral and neurochemical changes.
ZZL‑7 targets the SERT‑nNOS protein complex in the dorsal raphe nucleus, disrupting their interaction.
High blood‑brain barrier permeability allows quick access to target brain regions.
Rapid modulation of serotonergic signaling leads to fast‑onset behavioral and neurochemical changes.
Fast‑acting responses observed within hours in research models
Excellent blood‑brain barrier penetration for effective brain targeting
Selective disruption of SERT‑nNOS interaction without off‑target effects
| Feature | ZZL‑7 | Traditional Antidepressants |
|---|---|---|
| Onset Time | Hours | Days to Weeks |
| BBB Permeability | High | Variable |
| Mechanism | SERT‑nNOS Disruption | Various |
| Research Value | Novel Target | Established |
| Selectivity | High | Variable |